https://www.selleckchem.com/pr....oducts/Vorinostat-sa
Results The total number of lumbar discs with decreased SI increased from 23/130 (18%) to 92/130 (71%) - from 0.9 to 3.5 per subject during the follow-up. Distribution of DD changed from being mostly in L4 - L5 and L5 - S1 discs to being almost even between the four lowermost discs. Discs that had even slightly decreased SI at baseline were more likely to have severely decreased SI at follow-up, compared to healthy discs (57% vs 11%, p less then 0.001). Other degenerative changes were also more common in these discs. Severity of
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