https://www.selleckchem.com/sc....reening/kinase-inhib
Depletion of intracellular polyamines reduced GATA3 expression but increased IL-9-producing CD4+ T cells under both Th2 and Th9-skewing conditions. Furthermore, oral administration of DFMO increased IL-9-producing CD4+ T cells in small intestine in mice. Thus, our data indicate that polyamines play a critical role in the regulation of the Th2/Th9 balance.The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. In the absence of a licensed vaccine
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