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5 wt% clove essential oil was added to the system. The encapsulating systems had predominantly gel-like property with maximum elastic modulus of 411 Pa. Furthermore, the emulsion-filled CNF hydrogels with the addition of clove essential oil up to 0.5 wt% indicated good cell viability rates (74-101%) to human gingival fibroblast cells. The newly developed clove essential oil emulsion-filled CNF hydrogel shows desirable cytocompatibility characteristics and can be considered as an alternative scaffold for tissue engineering applications. S
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