https://www.selleckchem.com/pr....oducts/nedisertib.ht
Among the type1 diabetes patients, the glucagon response showed no differences between the subgroups based on diabetes duration (5 vs ≥5years) and fasting C-peptide levels (0.10 vs ≥0.10nmol/L). The changes in plasma glucose from fasting to 30min were positively correlated with those in glucagon, but not C-peptide, irrespective of diabetes duration and fasting C-peptide levels in patients with type1 diabetes. The dysregulated glucagon likely contributes to postprandial hyperglycemia independent of the residual β-cell function
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