https://www.selleckchem.com/pr....oducts/atglistatin.h
SIGNIFICANCE KRAS is the most frequently mutated oncogene. Here, we describe new preclinical models that mimic tissue-selective KRAS mutations and show that each mutation has distinct cellular consequences in vivo and carries differential sensitivity to targeted therapeutic agents.See related commentary by Kostyrko and Sweet-Cordero, p. 1626.This article is highlighted in the In This Issue feature, p. 1611. Alcohol-related vehicle crashes pose a significant challenge to public health in suburban communities. The Evesham Saving Lives
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