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05). Besides, serum levels of IL-2 and IL-6, percentages of CD3 CD4 T lymphocytes and ratio of CD4 /CD8 in peripheral blood were elevated in high- and medium-dose EEVLB groups compared with the model group (P0.05). Also, upregulation of caspase-3 and downregulation of Bcl-2 were observed at protein levels in the high-dose EEVLB group (P0.01). EEVLB exhibits promising antitumor activity in vivo. This effect might be due to activation of apoptotic signaling pathway, increase of cytokine levels and enhancement of immune function in
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