https://www.selleckchem.com/pr....oducts/abbv-cls-484.
Significant correlations between elevated PHB1 and TRAF6 expression and distant metastasis were observed in patients with oral cancer. Collectively, we elucidated a novel mechanism governing anoikis. Our data also indicated that TRAF6 and PHB1 are potential therapeutic targets for tumor cells disseminating in the circulation. Our data implicate that PHB1 competes with XIAP for binding to TRAF6 and confers anoikis resistance to tumor cells. Our data implicate that PHB1 competes with XIAP for binding to TRAF6 and confers anoikis resi
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