Cover Story: Joe Kiani and the Audacity to Care: Reflections on Principle, Persistence, and Patient-Centered Innovation

Joe Kiani stood before the packed ballroom at LSI USA ’25 in Dana Point with a speech in hand. But he never delivered it. Instead, he told a story—unscripted, emotional, raw. It was a story not just of companies built or innovations commercialized, but of the angels who showed up along the way, the systems that tried to shut him out, and the patients whose lives gave meaning to every battle he fought.

“We have a real responsibility and an opportunity to change people’s lives for the better,” Kiani tells the audience. “And it’s not easy. But it’s everything.”

This is the story of Joe Kiani—a founder whose first company, Masimo, grew from a “garage startup,” as he calls it, to a global medical technology powerhouse, and whose new company, Willow Laboratories, is set on reimagining diabetes care. But more than that, it’s the story of a leader guided not by market share or IPO timing, but by something far more enduring: the North Star of doing what’s best for patient care

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