https://www.selleckchem.com/pr....oducts/salinosporami
By affecting both tumor cells and the tumor microenvironment, PRMT5 inhibitors mayserve as effectiveanti-cancer agents, especially when combined with immune therapies. In this review, we summarize current knowledge on the role of PRMT5 in cancer development and progression, including its functions and underlying mechanisms. In addition, we highlight the rapid development of PRMT5 inhibitors and summarize ongoing clinical trials for cancer therapy. By affecting both tumor cells and the tumor microenvironment,
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