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05, and two (rs187989831 and rs12100172) with MAF less then 0.01. Conditional analysis within genome-wide significant loci revealed four loci (p less then 1 × 10-5) with multiple independent risk variants, while GenEpi analysis identified SNP-SNP interactions in seven genes. In addition to identifying novel risk loci for PD, these results demonstrate that WGS-based imputation and analysis of existing exome genotype data can identify novel intronic and intergenic SNP effects associated with complex disease risk.This literature re
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