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To determine the impact of infarct site combinations on prognosis of small subcortical infarction (SSI) by classifying the infarcted perforator area in relation to the anatomical structures that surround and/or involve the corticospinal tract. Consecutive patients with SSI ≤24h from onset to initial magnetic resonance imaging (MRI) and≤14days from onset to second MRI were included. Infarct sites were defined as follows caudate head, lentiform (L), corona radiata (CR), posterior limb and genu of the internal capsule (IC), thalamus, and
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