https://www.selleckchem.com/pr....oducts/combretastati
Background The physiological mechanisms underlying the development of respiratory hypersensitivity to cisplatin (CDDP) are not well-understood. It has been suggested that these reactions are likely the result of type I hypersensitivity, but other explanations are plausible and the potential for CDDP to induce type I hypersensitivity responses has not been directly evaluated in an animal model. Objectives and Methods To investigate CDDP hypersensitivity, mice were topically sensitized through application of CDDP before being ch
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