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Among them emerged 5-(3-cyano-5-(trifluoromethyl)phenyl)furan-2-carboxylic acid (IV), endowed with comparable inhibitory properties to the previous leads, but a better antitubercular activity, which is a key issue in MbtI inhibitor research. Therefore, compound IV offers promising prospects for future studies on the development of novel agents against mycobacterial infections.In the eye lens cell membrane, the lipid composition changes during the aging process the proportion of sphingomyelins (SM) increases, that of phosphatidylcholines
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