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The evolved SPE-HPLC-MS/MS treatment (in the sewage-based epidemiology strategy) allowed when it comes to simultaneous, selective, very sensitive and painful, accurate (recoveries ≥ 80.1%) and accurate (CV ≤ 8.1%) dedication of new and classic psychoactive substances in wastewater samples. This research is described as brand-new systematic elements, especially in regards to the freeze-thaw and post-preparative stability regarding the selected psychoactive substances. This is actually t
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