https://www.selleckchem.com/products/TWS119.html
6% vs 24.2% vs 25.0%, P = .028), compared to those with I/M (n = 66) and I/I (n = 8 PNPLA3 genotype. The association of I148M homozygosity with lower e-GFR levels (P less then .0001) and higher risk of CKD (adjusted-odds ratio 6.65; 95% CI 1.65-26.8, P = .008) was independent of liver disease severity (as detected by liver stiffness ≥7kPa) and other risk factors. PNPLA3 mRNA expression was greatest in liver and renal cortex, and podocytes showed high PNPLA3 mRNA and protein levels, comparable to that of hepatocytes and hepatic stellate
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