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In contrast, the precision of HybridSucc ended up being 17.84%-50.62% a lot better than that of other existing tools. Utilizing HybridSucc, we carried out a proteome-wide prediction and prioritized 370 cancer mutations that change Ksucc states of 218 important proteins, including PKM2, SHMT2, and IDH2. We not merely developed a high-profile tool for predicting Ksucc sites, additionally produced of good use candidates for further experimental consideration. The online solution of Hybr
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