https://www.selleckchem.com/pr....oducts/Sapogenins-gl
Blocking ESCRT protein activity increases tumor cell susceptibility to cytotoxic T-cell killing.During the American Association for Cancer Research Annual Meeting 2022, researchers discussed ways to improve chimeric antigen receptor T-cell therapy's efficacy in solid tumors. These included sussing out differences between solid and blood cancers in their susceptibility to CAR T cells' cytotoxicity, taking a modular approach to engineering next-generation agents, and building in breaks for exhaustion-prone CAR T cells to res
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