https://www.selleckchem.com/products/ho-3867.html
N -methyladenosine (m A), the most prevalent and dynamic posttranscriptional methylation modification of mammalian mRNA, is involved in various biological processes, but its role in liver regeneration has not been characterized. We first conducted transcriptome-wide m A mRNA sequencing and characterized the expression pattern of m A in regenerating mouse liver. Next, we generated hepatocyte-specific Mettl3- or Mettl14-deficient mice and investigated their role in liver regeneration. A series of biochemical experiments invitro and invivo
Gefällt mir
Kommentar
Teilen
