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None had ( or (C) genes. F101L and G4D/K/R or T150A were the main substitutions of ribosomal protein L4, L3, respectively. We found one isolate co-contained and and another isolate co-contained and (D), but they were not resistant to linezolid. Among 20 -positive strains, ST-16 was the main type. Two main variants KD (T112K, Y176D) and RDK (I104R, Y176D, E256K) slightly raised enterococci's MIC of linezolid. OptrA exists in linezolid non-resistant enterococci with diverse amino acid substitutions. The variants play different roles in changing the MIC of l
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