https://www.selleckchem.com/pr....oducts/PF-2341066.ht
© 2018 Published by Elsevier B.V. on behalf of Shenyang Pharmaceutical University.The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule (Avodart®). The effect of cyclodextrin on enhancing the aqueous solubility of dutasteride was investigated, after which the formulation was further optimized with solubilizing polymer and surfactant. Among the cyclodextrins tested, the highest solubility was observed when dutasteride was complexed with γ-cyclod
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