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In this work, we employ the extension of Mawhin's coincidence degree by Ge and Ren to investigate the solvability of the p-Laplacian higher-order boundary value problems of the form ( w ( t ) ϕ p ( x ( n - 1 ) ( t ) ) ) ' = h ( t , x ( t ) , ⋯ , x ( n - 1 ) ( t ) ) , 0 0 for all t ≥ 0 , ϕ p s = | s | p - 2 s . Genistein is an isoflavone compound that has been proven to have anticancer activity and is capable of binding to estrogen β receptors with Selective Estrogen Receptor Modulators (SERMs) properties, and has a strong affinity to inhi
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