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The sex-specific and age-specific cut-offs for NT-proBNP had higher specificity for subclinical HF compared with the previously established single cut-off 125pg/mL. Age-specific cut-off for hs-troponin T (18ng/L) for men ≥60years had also higher specificity than the single cut-off 14ng/L. These cut-offs had high specificity, but low sensitivity, that makes hs-troponin T and NT-proBNP good biomarkers to rule in HF in case of a positive test, but not good enough to rule out all unrecognized HF due to false negative results. N-terminal pro-b
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