https://www.selleckchem.com/ph....armacological_epigen
Our phototoxic protein-photosensitizer-conjugates show excellent photodynamic activity against a human colorectal adenocarcinoma cancer cell line (HT-29) with cell viabilities of 7.7±0.5 % (IC50 8.76±2.14 μM) and 1.7±1.9 % (IC50 8.48±5.11 μM) for BSA and HAS, respectively, when irradiated with 20 J cm-2 of white-light. Importantly, neither of the conjugates was found to possess any significant "dark" toxicity even at concentrations of 100 μM. Furthermore, the natural fluorescent properties of the bioconjugates allowed for the
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