https://www.selleckchem.com/pr....oducts/NVP-AUY922.ht
Patients with AKI had longer circulatory pulmonary bypass (CP time, and male patients with AKI had higher ET-1 levels than those without AKI. In multivariable logistic regression analysis, the preoperative ET-1 level and CPB time were the independent determinants of AKI, even adjusted by age, sex, and BMI. The preoperative GDF-15 level, CPB time, and RCC transfusion were independent determinants of 30-day mortality plus morbidity. Preoperative GDF-15 and ET-1 levels as well as intraoperative factors such as CPB time may be helpful
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