https://www.selleckchem.com/pr....oducts/pkr-in-c16.ht
We recently reported the dose-dependent therapeutic effect of 211At-NaAt in differentiated thyroid cancer xenograft models. In the present study, we evaluated the radiation-induced toxicity of 211At-NaAt using detailed hematological, biochemical, and histological analyses. Biodistribution of 211At-NaAt was measured in normal ICR mice (n = 12), absorbed doses in the major organs were calculated. Groups of ICR mice (n = 6 were injected with 0.1 MBq or 1 MBq of 211At-NaAt, using saline as the control group (n = 3. Body weight and fo
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