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Finally, we show that the application of fluid shear stress allows the long-term culture of this intestinal epithelium. Our device represents a new biomimetic tool that captures key features of the gut complexity and could be used to study gut pathophysiology.A novel DNA-microgel hybrid system with dual thermal responsiveness is introduced uitilizing covalent coupling of single stranded DNA (ssDNA) to thermoresponsive microgels (μGs). The spatial distribution of the coupling sites for the ssDNA was characterized with 3D superresolution fl
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