https://www.selleckchem.com/pr....oducts/ly3214996.htm
Conclusions The shift from early wound healing efforts to a fibrotic scar with densely packed collagen within the skeletal muscle occurs around 21 days after VML injury through dogmatic synchronous reduction of collagen III and increase in collagen I. Thus, there appears to be an early window for therapeutic intervention to prevent pathologic fibrous tissue formation, potentially by targeting CCN2/CTGF or using decorin as a therapeutic.Resistance against clinically approved anticancer drugs is the main roadblock in cancer treatment. D
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