https://www.selleckchem.com/pr....oducts/sch-527123.ht
In addition, TMEM88 upregulation markedly retarded the tumor growth of thyroid cancer cells in vivo using xenograft models associated with downregulation of active β-catenin expression. Taken together, our findings demonstrated that TMEM88 overexpression impeded the proliferation and invasion of thyroid cancer cells through downregulation of Wnt/β-catenin signaling. These data indicate a potential tumor-suppressive function of TMEM88 in thyroid cancer. Our study highlights a key role for TMEM88 in regulating Wnt/β-catenin signaling d
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