https://www.selleckchem.com/pr....oducts/pd-1-pd-l1-in
Overexpression of legumain is closely associated with tumor proliferation, invasion, and metastasis. Because of its intrinsic properties, such as high sensitivity and resolution, positron emission tomography (PET) has become an effective imaging technique for early diagnosis, treatment response prediction, and monitoring. Herein, two legumain-targeting radiofluorinated smart probes ( 18 F-2 and 18 F-3) as well as a control probe ( 18 F-1) were specifically designed for PET imaging of legumain activity in tumors. 18 F-1, 1
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