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The present review will illustrate the main potential mechanisms of MS pathogenesis possibly associated with viral infections and viruses currently used to study demyelination in animal models. Then the viruses most strongly linked with MS will be discussed, in the perspective that more than one virus might have a role, with varying degrees of interaction, contributing to MS heterogeneity. © 2020 Published by Elsevier Ltd.The field-based studies on sand flies are not adequate to uncover information required for the control of the leish
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