https://www.selleckchem.com/products/BIBW2992.html
In all of these catalysts, the rate-determining step (RDS) of cyclohexane borylation needs a larger ΔG°‡ than the RDS of methane borylation because the more bulky cyclohexyl group induces larger steric repulsion with the ligand than methyl. One reason for the worse chemoselectivity of the Ir catalyst is its less congested transition state of the reductive elimination of borylcyclohexane. Herein, use of a strongly electron-donating ligand consisting of pyridine and N-heterocyclic carbene with bulky substituents is computationally propos
Мне нравится
Комментарий
Перепост
