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The clinical relevance of small right-to-left shunt (RLS) in young patients with cryptogenic stroke is unknown. We aimed to analyze and understand the relationship between cryptogenic stroke and small RLS by studying specific cases. Clinical data from two cases of small RLS-related cryptogenic stroke in young patients were collected prospectively and analyzed. We followed up the patients for 1 year after discharge. . A 50-year-old man was admitted for slurred speech and right hemiplegia and was diagnosed with acute cerebral infarct
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