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CsA alone had no impact on the apoptosis price. Whenever ERK signaling inhibitor PD98095 was used, there is the same outcome that mitophagy had been paid down though in contrast with CsA the apoptosis price was also diminished in contrast to NaAsO2 alone. This outcome, combined with the increased levels of ERK sized right here in response to NaAsO2, shows that ERK activation is a moment key molecular response to NaAsO2 through the activation of both apoptosis and mitophagy. Therefore the outcome wi
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