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Appropriately, a calibration bend for each contaminant group had been built, causing correlation coefficient values greater than 0.99. Also, lower limits of recognition and measurement had been obtained, and accuracy (repeatability and advanced precision) attained results with a coefficient of variation lower than 15 percent. Medication recovery from skin samples was more than 70 %, fulfilling the suggestions. Also, the bioanalytical method had been successfully tested in in vitro
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