https://www.selleckchem.com/products/agk2.html
IRF3 and type I interferon receptors (IFNARs) are required for the STING-driven enhancement of T 1 cell differentiation. However, STING activation favors T 9 cell differentiation independently of the IFNARs/IRF3 pathway but through mammalian target of rapamycin (mTOR) signaling, underscoring that STING activation differentially affects the fate of distinct CD4 T-cell subsets. The therapeutic effect of STING activation relies on T 1 and T 9-derived cytokines, and STING activation enhances the antitumor activity of T 9 cells upon adoptive tr
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