https://www.selleckchem.com/pr....oducts/pirfenidone.h
Label-free methods for quantifying myelination can reduce expense, time, and variability in results when examining tissue white matter pathology. We sought to determine whether the optical birefringent properties of myelin could be exploited to determine myelination status of white matter in tissue sections. Sections of forebrains of mice (normal, and treated with cuprizone to cause demyelination) were examined by birefringence using a birefringence imaging system (Thorlabs LCC7201), and results compared with sections stained using
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