https://www.selleckchem.com/pr....oducts/avelestat-azd
5 μg/mL for linezolid. Mean concentrations in plasma, collected 100-510 min after the preoperative dosing, were 10.43 ± 4.83 μg/mL (range 3.29-22.26 μg/mL), and median concentrations in bone were 3.93 μg/mL (range 0.61-16.34 μg/mL). The median bone/plasma penetration ratio was 0.42 (range 0.14-0.95 μg/mL). Linezolid concentration in bone had a linear correlation with the drug concentration in plasma (r = 0.7873, p 0.0001), while plasma concentration could explain 61.98% of the variation of concentration in bone (R = 0.619
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