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The Most Effective ADHD Medication For Adults Most of the medications used to treat ADHD are classified into two groups: stimulants and nonstimulants. The stimulants like methylphenidate (Provigil) and amphetamines act by increasing the activity in areas of the brain responsible for the behaviour and attention. -stimulants like atomoxetine (Strattera) as well as Guanfacine (Intuniv) and clonidine (Kapvay), work slower than stimulants but can help improve concentration, focus and impu
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