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Reported let me reveal a straightforward means for synthesizing acyclic diketene acetal monomers from diols and vinyl ether, and their particular polymerization with a diol to very first synthesize PAOEs. The PAOEs rapidly hydrolyze at lysosomal pH. By using a cationic lipid, ovalbumin, a model vaccine antigen was efficiently filled into PAOEs nanoparticles making use of a double emulsion strategy. These nanoparticles efficiently delivered ovalbumin into the cytosol of dendritic c
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