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The active oxygen content of tissues was also significantly reduced (P0.05). OI reduced the accumulation of neutrophils and secretion of inflammatory factors in LPS-induced ALI (P0.05). At the cellular level, OI also reduced oxidative stress and inflammation. Intervention with OI was also observed to upregulate the expression of nuclear factor erythroid 2-related factor-2 (Nrf-2) and Nrf-2 target genes in the lung tissue and RAW264.7 cells. OI alleviates LPS-induced ALI. Moreover, the antioxidant and anti-inflammatory effects of O
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