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https://www.selleckchem.com/pr....oducts/pf-06463922.h
These results aim to develop a better understanding of the relationship between PIL properties and structure, to help design ILs with optimal properties for applications.Microglial inflammation driven by the NLRP3 inflammasome contributes to brain disease and is a therapeutic target. Most mechanistic studies on NLRP3 activation utilise two-dimensional pure microglial cell culture systems. Here we studied the activation of the NLRP3 inflammasome in organotypic hippocampal slices, which allowed us to investigate microglial NLRP3 activ