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No multi-aberrant and polyploid cells were observed. In all variants of the experiment, only chromatid-type chromosome aberrations with single fragments were detected in the spectrum of chromosome aberrations. The severity of this effect had an inverse dose dependence with a decrease in the dose of Ivin, the cytogenetic effects of Dioxidine decreased to a greater extent than with high doses of Ivin. The high antimutagenic effect of Ivin was confirmed, which is expressed to a greater extent when it is combined with Dioxidine than with Cyclophosphamid