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auris were much higher than second-generation azoles and echinocandins. Ravuconazole was active against all the C.auris isolates and as effective as isavuconazole, posaconazole and echinocandins while showed a better antifungal activity than itraconazole, voriconazole to C.auris. For vaginal Candida isolates, the proportion of ravuconazole-resistant isolates is 0.19% (1/525). Ravuconazole was in good active against C.auris and vaginal Candida isolates, which suggested ravuconazole could be used in the treatment of drug-resistant candid