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It had been seen that the tissue matrix had a small influence on the performance of dropletProbe MS for the restricted set of tested substances as soon as an optimized extraction solvent had been identified. A general beginning removal solvent of 11 acetonitrile/water (vv) had been identified to effortlessly extract the test group of substances from numerous areas. Next, the enhanced problems were utilized to map the circulation of the drug diclofenac and its particular metabolites in whole-body mouse parts. The g