https://vericiguatmodulator.co....m/cutaneous-adnexal-
To better characterize RAS-driven signaling, we recently developed a chemical genetic system for activating endogenous RAS with a little molecule. In this part, we explain the usage chemically inducible activator of RAS (CIAR), a single-protein, chemical genetic system that allows the fast and dose-dependent activation of endogenous RAS. practices in this chapter additionally describe the validation of RAS activation with CIAR through the ana
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