https://www.selleckchem.com/pr....oducts/chir-99021-ct
Coadministration of atorvastatin showed remarkable improvement in the histopathological picture with a significant increase in Ki-67 and Bcl-2, a significant decrease in NF- B protein and gene expression, and a significant increase in Nrf2 gene expression. Atorvastatin substantially attenuates CPT-11-induced oral mucositis through the initiation of the antiapoptotic gene, modulation of the inflammatory, and antioxidant gene expression. Atorvastatin substantially attenuates CPT-11-induced oral mucositis through the initiat