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ort analysis of patients with CHF and CKD, we identified 13 independent variables associated with in-hospital mortality using LASSO logistic regression. RDW, AG, and CRRT were reported to play a significant role in in-hospital mortality among patients with CHF and CKD for the first time. Based on a simplified model including 13 variables, a nomogram was drawn to predict the risk of in-hospital mortality. In comparison with SAPS II and LODS, the nomogram model performed well. In this retrospective cohort analysis of patients with CHF and CK