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ADHD OTC Medication ADHD medications can help children with ADHD manage symptoms and improve their functioning. It is important to monitor the effects of these medications. Your doctor may ask you or your child fill out behavior rating scales, observe changes, and look for side effects. The adverse effects of stimulant medications include stomach upset, reduced appetite and antics. They may also increase heart rate and blood pressure. Methylphenidate Methylphenidate is a FDA-approved drug for attention deficit h