https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Instead, we found that cytosolic reductive states caused by a mislocalized catalase in the peroxisome-deficient cells induce the elevation in BDNF secretion. Our results suggest that peroxisome deficiency dysregulates neuronal axogenesis by causing a cytosolic reductive state in astrocytes. We conclude that astrocytic peroxisomes regulate BDNF expression and thereby support neuronal integrity and function. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.We previously reported that
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