https://www.selleckchem.com/pr....oducts/INCB18424.htm
Analyzing protein kinase C (PKC) alpha, iota, and zeta as well as levels of Mxi-2 and Vim3 in regressive clear cell renal carcinomas (ccRCCs) and urine samples. Fresh samples of ccRCCs (predominantly pT1a/b) with different degrees of regression (10%, 30%, 50%, and 70%) vs normal renal tissue and oncocytomas were studied by Western blot, using antibodies of different PKC isoforms. Urine samples from these tumors were analyzed by ELISA (PKC isoforms, Mxi-2, and Vim3). With increasing degree of regression beyond 10%, nuclear Mxi-2 an
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